If you have been researching collagen stimulating treatments, you have probably come across all three of these names and wondered what actually separates them. It is a fair question. All three work with your body rather than against it, and all three sit within what I call the Regenerate edit: treatments that rebuild rather than simply fill. But they are not interchangeable, and the right choice depends entirely on what your skin needs. Here is how I think about the differenc

Ask ten people what a retinoid is and you'll get ten different answers. Anti ageing miracle. Purging nightmare. Something a dermatologist mentioned once that never got followed up on. The truth sits somewhere more useful than the marketing, and it starts with understanding that "retinoid" is a family of ingredients, not a single one. This guide walks through what retinoids actually are, how retinol, retinal and retinoic acid relate to each other, and how to introduce one with

by Dr Vix Manning Nora Ephron put it better than most of us ever will. "Oh, the necks," she wrote. "There are chicken necks. There are turkey gobbler necks. There are elephant necks. There are necks with wattles and necks with creases... Our faces are lies and our necks are the truth." "Our faces are lies and our necks are the truth. You have to cut open a redwood tree to see how old it is, but you wouldn't have to if it had a neck." — Nora Ephron, I Feel Bad About My Neck

If you've spent any time in aesthetics recently, you'll have noticed a shift. We're moving away from adding volume with fillers and towards something far more interesting: teaching your own skin to rebuild itself. JULÄINE is at the sharp end of that shift, and it's one of the treatments I get asked about most in clinic. What Actually Is JULÄINE? JULÄINE is a next generation PLLA (poly-L-lactic acid) collagen biostimulator, developed by Nordberg Medical in Sweden. It's injecte

A reader's question reveals the real divide in how we approach health. A reader of Busting the Code to Ageing emailed me last week. She wanted to know whether people who engage with the book tend to focus on the practical interventions, the testing strategies, the supplementation protocols or whether they engage with the broader argument: that health should be understood proactively, not reactively. It's a sharper distinction than it might first appear, and she was right to d

As a longevity doctor I spend my days looking at blood results, cellular markers, and the slow, silent creep of inflammaging. My world is built on biomarkers, mechanisms, and measurable outcomes. So when I started taking a saffron supplement, I did not do it because it sounded nice. I did it because the clinical data was compelling and I wanted to know, in my own physiology, whether it worked. Let me explain why I was looking in the first place. Like many people running a bus

The Root Cause Reset: Why Your Gut Health is the Secret to Ageing Well Discover how gut health impacts inflammation, skin, and ageing. Dr Victoria Manning explains the gut microbiome, leaky gut, and how to restore balance. The Root Cause Reset: Why Your Gut Health is the Secret to Ageing Well If you have been struggling with fatigue, skin breakouts, brain fog, or stubborn weight, you might be looking for answers in the wrong places. For years, we have treated symptoms. We p

Does your bedroom have a glowing alarm clock, a streetlamp shining through the curtains, or a standby light on the TV? If you can see your hand in front of your face at night, your bedroom isn't dark enough—and it is actively suppressing your body's ability to repair itself. When was the last time you could honestly say you had a truly good night's sleep? A night where you didn't lie there staring at the ceiling, and actually woke up feeling refreshed? If that sounds like a r

Forget The Walking Dead- the most persistant zombie apocalypse is happening inside your body right now. In the world of longevity science, there’s a group of cells that are quietly undermining your health, recovery, and how you age. They don’t send out a dramatic announcement or cause sudden symptoms. Instead, they linger, creating the perfect biological environment for inflammation, dysfunction, and accelerated ageing to thrive. Scientists call them senescent cells. Most of

We're all familiar with the usual suspects when it comes to skin ageing: sun exposure, smoking, stress. But what if one of the most significant — yet least-discussed — drivers of ageing is happening right on your dinner plate? It's a process called glycation, and it's essentially caramelising your skin from the inside out. As an aesthetic and longevity doctor with over two decades of clinical experience, I've seen firsthand how profoundly lifestyle impacts the way we age. And

As many of you know, I’ve been wearing a Continuous Glucose Monitor (CGM) as part of our new MAP Health Longevity testing. It’s been fascinating to see in real-time how my body responds to food, exercise, and sleep. But the most shocking discovery? My blood sugar spiked to its highest point all week, and I hadn’t eaten a single thing. What happened? Life happened. It was a day filled with back-to-back patients, culminating in a flat tyre on the way home. As I waited for the A

Have you ever looked in the mirror and felt like you’re aging faster than you should be? You’re doing all the right things—or so you think—but new lines seem to appear overnight, your skin lacks that youthful bounce, and you just look… tired. If this sounds familiar, you might be dealing with a silent saboteur: inflammaging . le most important factor in how well we age. So, let’s break down what it is, why it’s suddenly everywhere, and what you can actually do about it. What

By Dr. Vix Manning Have you ever felt like you’re doing everything right—eating well, exercising, even taking your supplements—but still struggle with nagging joint pain, brain fog, or a general sense of fatigue you just can’t shake? I’ve been there. As a doctor, I thought I had my health dialled in. I ate a healthy diet, took a daily fish oil supplement, and considered myself well-informed. So, you can imagine my shock when I tested my own omega-6 to omega-3 ratio and the re

And why this changes everything about medical weight loss Before I get into my own results, a quick note on the testing I’m referring to. What is MAP Health? MAP Health is a personalised health programme built around your body — not generic advice. It combines three powerful data sources to create a plan you can actually follow: DNA (genetics): your blueprint — how you’re wired to respond to nutrition, exercise, sleep and recovery Blood biomarkers: what’s happening in your

When it comes to wellness, finding someone who truly understands the science behind health and the art of living well is a game changer. That’s exactly what I discovered when I met Dr Vix Manning - a passionate expert dedicated to helping people conquer inflammation, age gracefully, and build thriving wellness businesses. Today, I want to share her inspiring approach and practical tips that can transform your health and entrepreneurial journey. Why Wellness Expert Dr Manning

A new “Lancet” study has confirmed what many of us are now seeing in real life: most people who stop GLP-1 medication regain weight — and not just a bit. On average, around 5.6kg within months of stopping. For transparency: I’ve just stopped my own Mounjaro due to nocturnal hypoglycaemia; found when I had my glucose monitor on in December with MAP Health. So I’m writing this not only as a doctor, but as someone navigating this exact transition right now. The reality chec

The twilight zone space between Christmas and New Year is deceptively challenging for your physiology. Late nights blur into lazy mornings, sugar and alcohol consumption peaks, travel disrupts routine, and even positive family gatherings add stress to your nervous system. You might notice: Waking bolt upright at 3–4am, mind racing Feeling simultaneously exhausted and unable to settle in the evening Reaching for carbs and sweet snacks more than usual Brain fog, muscle aches,

Aging is inevitable, but decline is optional. As a doctor and author of Busting the Code to Ageing: How to Win the Inflammation Game , my mission has always been to empower people to understand the root causes of ageing and take control of their health. That’s why I’m excited to announce my partnership with Vivorum—a brand that shares my obsession for evidence-based, cellular-level longevity. Why Vivorum Resonates With My Philosophy Vivorum stands out in a crowded market beca

When I first started my journey into health and wellness, I was amazed at how quickly the landscape was evolving. Every year, new technologies and discoveries seem to pop up, promising to help us live longer, feel better, and age gracefully. If you’re like me, always curious about the latest trends and breakthroughs, you’ll love diving into some of the most exciting innovations shaping our well-being today. Let’s explore these game-changers together and see how they can fit i

Let me ask you a question. When was the last time you woke up feeling truly energised; clear-headed, light, focused? Most people I work with, executives, professionals, even doctors can’t remember. They assume it’s just what happens with age. But what if that slow fade in energy, focus, and drive isn’t ageing at all? What if it’s inflammation? I often describe it like this: imagine a small campfire burning in your body. When it’s contained, it’s useful, that’s normal inflamma