Wegovy: Can a Weight-Loss Drug Really Turn Back the Clock on Ageing?

It is great to see real data coming through!

A recent New Scientist article has brought to light a groundbreaking clinical trial suggesting that Wegovy (semaglutide)—a GLP-1 agonist commonly prescribed for obesity and type 2 diabetes—may do more than help with weight loss. The study’s results hint at the possibility of slowing, and even reversing, biological ageing.

So What Did the Study Show?

In a trial involving 84 participants, those taking semaglutide saw their biological age decrease by an average of 3.1 years, with some organs appearing nearly 5 years younger after treatment. These findings are not just statistically significant—they’re potentially transformative for longevity and anti-ageing medicine.

How Might Wegovy Influence Ageing?

The benefits of Wegovy seem to extend far beyond the number on the scale. According to the study:

• Reduces chronic inflammation: Chronic, low-grade inflammation (“inflamm-ageing”) is a central driver of biological ageing.

• Improves metabolic health: Better metabolic function is closely linked to slower cellular and organ ageing.

• Enhances organ function: Some organs in study participants appeared years younger after the intervention.

This aligns with a growing body of scientific evidence: metabolic health and inflammation are at the heart of the ageing process. By targeting these core pathways, GLP-1 agonists like Wegovy could represent a new frontier in age management.

Connecting the Science: "Busting the Code to Ageing"

In my book, Busting the Code to Ageing: How to Win the Inflammation Game, I explore in depth how chronic inflammation underpins most age-related decline. The latest research on Wegovy reinforces this message: by reducing inflammation and optimising metabolic pathways, we can meaningfully slow the biological clock.

Key strategies from my book that complement these findings:

• Test-based, personalised nutrition: Target inflammation at its source with precision.

• Evidence-based supplementation: Support your body with omega-3s, gut health nutrients, and more.

• Lifestyle interventions: Reduce stress, improve sleep, and support metabolic health for optimal longevity.

Wegovy’s results are a powerful proof-of-concept for my core philosophy: address inflammation, and you can change the trajectory of your healthspan.

What Does This Mean for You?

Wegovy is not a magic bullet, and it’s not suitable for everyone. However, it’s an exciting example of how modern science is rapidly expanding our toolkit for healthy ageing. For most people, the foundation remains:

• Personalised nutrition, guided by testing,

• Targeted, high-quality supplementation,

• Consistent, sustainable lifestyle changes.

If you’re interested in the latest science on inflammation, ageing, and practical strategies to optimise your health, you’ll find clear explanations and actionable advice in my new book, Busting the Code to Ageing: How to Win the Inflammation Game—available now on Amazon.

Get Your Copy

Want to learn more about your own inflammation status and how to optimise your longevity? Explore my resources on test-based nutrition and anti-inflammaging solutions.