The Regenerating Edit
Polynucleotides
The Healers of the Skin
Derived from purified salmon or trout DNA, polynucleotides are not fillers but cellular repair agents. They calm inflammation, activate fibroblasts, and restore compromised skin at the molecular level, improving texture, tone, and resilience. They do not fill the face; they repair it quietly, molecule by molecule. It is a fast growing treatment, valued for its gentle, restorative effect, and combines beautifully with other skin boosters.
How it works
Once injected, polynucleotides act as a signal to your skin cells, encouraging repair, reducing inflammation and supporting the production of new collagen and elastin. They also improve local blood supply and have a strong hydrating effect, helping the skin hold onto moisture more effectively. Over a course of treatment, this leads to smoother, plumper, more resilient skin with an improved tone and texture.
Who it is for
Polynucleotides are excellent for under eye thinning and dark circles, redness prone or sensitive skin, and post acne scarring and fragility. They are a gentle option for those wanting to improve skin quality without adding volume. They work especially well combined with other skin boosters as part of a wider skin quality plan. It is not suitable during pregnancy or breastfeeding.
What to expect
Most people have a course of three sessions, around 2 to 4 weeks apart, each taking around 30 minutes. Skin quality improves progressively over the course, with results typically lasting several months, after which occasional maintenance treatment is recommended to sustain the improvement.
Dr Vix Manning's approach
Dr Vix Manning uses polynucleotides as part of her foundations before decorations philosophy, often recommending them to repair and prepare skin that has become stressed, thin or depleted, before considering other treatments. Her gentle, considered technique makes this a particularly good option for sensitive areas and for anyone newer to injectable treatments.
Frequently asked questions
What do polynucleotides actually do?
They help repair and calm the skin at a cellular level, improving hydration, texture and resilience rather than adding volume.
How many sessions will I need?
Most people have a course of three sessions, around 2 to 4 weeks apart.
How long do results last?
Improvements typically last several months, with occasional maintenance treatment recommended to sustain results.
Is the treatment painful?
Most people find it comfortable, with only mild, temporary swelling or small bumps at injection sites.
Can polynucleotides be used under the eyes?
Yes, this is one of the areas where they are particularly effective and gentle.